Polypharmacy entails taking of 5 or more medicines. Generally, polypharmacy in the elderly occurs because of three factors: demographic factors, health factors, and access to healthcare. It is more common among older patients and has potential harms such as drug interactions and drug toxicity. Polypharmacy is an area of concern for elderly because of several reasons. Elderly people are at a greater risk for adverse drug reactions (ADRs) because of the metabolic changes and reduced drug clearance associated with ageing; this risk is furthermore exacerbated by increasing the number of drugs used. Polypharmacy is linked to increased risk of adverse drug events in older people due to increased risk of drug interactions, lack of adherence to medication regimes, susceptibility of older people to side effects of medications, and physical changes related to ageing causing difficulties in taking medications as prescribed. One of the risk factors is frailty. Patients who are frail are more likely to be having many health conditions that can contribute to excessive polypharmacy. Another risk factor is multimorbidity (Card, 2016; Ersoy, 2018). Patients who have many chronic conditions may be have to take 5 or more medicines to manage their conditions. Obesity is another risk factor. Obese people may have risk factors for many health conditions such as diabetes, heart disease, and high blood pressure, among others (Ersoy, 2018). These conditions may make them to take many medicines to manage them, therefore resulting to polypharmacy. In the elderly, disorders that occur as a result of ageing, frequently require treatment, resulting in increased use of medications. Polypharmacy is common among the elderly and although it can be therapeutic in nature, is linked to adverse events such as falls.